The only nonhormonal FDA approved therapy for treating symptoms of menopause is Brisdelle. Brisdelle contains paroxetine, which is a selective serotonin reuptake inhibitor (SSRI) that has been shown in clinical trials to help reduce the frequency and severity of hot flashes associated with menopause.
Some key points about Brisdelle:
- Brisdelle is a low-dose form of paroxetine specifically formulated to treat moderate to severe hot flashes associated with menopause. The dose is 7.5 mg once daily at bedtime.
- In placebo-controlled clinical trials, Brisdelle was shown to reduce the frequency of moderate to severe hot flashes by up to 55% compared to placebo after 12 weeks of treatment. Many women experienced relief as early as 4 weeks after starting treatment.
Benefits of Brisdelle:
- Nonhormonal treatment option - Does not contain estrogen or progestin like some hormonal therapies.
- Clinically proven efficacy - Reduces frequency of moderate to severe hot flashes by ~50% based on randomized controlled trials.
- Favorable safety profile - Low incidence of side effects at 7.5 mg dose. Does not worsen nighttime hot flashes.
- Convenient dosing - Just one 7.5 mg tablet taken at bedtime. No need to take multiple times a day.
- FDA approved - Only nonhormonal therapy formally approved by the FDA to treat menopausal hot flashes.
Who is Brisdelle for?
Brisdelle may be a good option for women who:
- Want to try a nonhormonal therapy first
- Have contraindications to taking hormones like estrogen
- Experience moderate to severe hot flashes
- Have not gotten relief from lifestyle modifications like avoiding triggers
Potential side effects of Brisdelle include:
- Headaches
- Tiredness
- Nausea
In clinical trials, Brisdelle was shown to have a low rate of side effects at the 7.5 mg dose. Still, you should discuss your medical history and all medications you are taking with your healthcare provider before starting this or any new treatment.
Seeking treatment for menopause symptoms
If bothersome menopause symptoms like hot flashes are impacting your quality of life,
don't hesitate to seek treatment. There are both hormonal and nonhormonal options like Brisdelle that may provide relief.
*_Check in with_ ***Vitality Balance Clinic(https://Vitality Balance Clinic.com)***_- your local menopause and hormone therapy specialists. Their experienced healthcare team can help evaluate your symptoms, discuss the latest nonhormonal and hormonal treatment options that may be right for you, and put together a personalized treatment plan aimed at improving your quality of life._
Summary
- Brisdelle (paroxetine 7.5 mg) capsules are the only FDA-approved nonhormonal option to help relieve moderate to severe menopause-related hot flashes.
- Brisdelle has been shown in clinical trials to reduce hot flash frequency by up to 55% compared to placebo.
- When taken at bedtime, Brisdelle can help minimize night sweats and sleep disruptions related to hot flashes.
- If you're looking for a non-estrogen treatment for hot flashes, talk to your healthcare provider about whether Brisdelle may be an option. Discuss any health conditions and medications to ensure appropriate for your situation.
